Elucidation of structure and biosynthetic pathway of small molecules from human microbiome.
Characterization of small molecules-mediated bacterial signaling pathways
Discovery of lead compounds for new drug from natural sources
학력
2010-2015 : 성균관대학교 약학대학 약학과 약학박사
2006-2010 : 성균관대학교 약학대학 약학과 약학사
약력/경력
2020-현재 : 성균관대학교 약학대학 조교수
2016-2020 : 박사후연구원, 예일대학교 화학과 (미국)
2015-2016 : 박사후연구원, 성균관대학교 약학대학
학술지 논문
(2023)
Anti-Inflammatory, Neurotrophic, and Cytotoxic Oxylipins Isolated from Chaenomeles sinensis Twigs.
ANTIOXIDANTS.
12,
2
(2023)
Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis.
ARCHIVES OF PHARMACAL RESEARCH.
46,
1
(2022)
Anticancer and Anti-Neuroinflammatory Constituents Isolated from the Roots of Wasabia japonica.
ANTIOXIDANTS.
11,
3
(2022)
PTP1B and alpha-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation.
PHYTOCHEMISTRY.
197,
-
(2021)
Glycosylated constituents isolated from the trunk of Abies holophylla and their anti-inflammatory and neurotrophic activity.
PHYTOCHEMISTRY.
192,
1
(2021)
Configurational Assignment of a Flexible Benzo[g]isochromene Stereodiad from Rubia philippinensis and Inhibition of Soluble Epoxide Hydrolase Activity.
JOURNAL OF NATURAL PRODUCTS.
84,
9
(2021)
Escherichia coli small molecule metabolism at the host-microorganism interface.
NATURE CHEMICAL BIOLOGY.
17,
10
(2021)
Phenolic constituents from twigs of Aleurites fordii and their biological activities.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY.
17,
.
(2021)
Escherichia coli-Derived gamma-Lactams and Structurally Related Metabolites Are Produced at the Intersection of Colibactin and Fatty Acid Biosynthesis.
ORGANIC LETTERS.
23,
17
(2021)
Structural characterization of prenylated compounds from Broussonetia kazinoki and their antiosteoclastogenic activity.
PHYTOCHEMISTRY.
188,
188
(2021)
Stilbene oligomers from the stems of Parthenocissus tricuspidata and their potential anti-neuroinflammatory and neuroprotective activity.
TETRAHEDRON LETTERS.
71,
.
(2021)
Ergopyrone, a Styrylpyrone-Fused Steroid with a Hexacyclic 6/5/6/6/6/5 Skeleton from a Mushroom Gymnopilus orientispectabilis.
ORGANIC LETTERS.
23,
9
(2021)
Phenolic Constituents of Chinese Quince Twigs (Chaenomeles sinensis Koehne) and Their Anti-Neuroinflammatory, Neurotrophic, and Cytotoxic Activities.
ANTIOXIDANTS.
10,
4
(2021)
A community resource for paired genomic and metabolomic data mining.
NATURE CHEMICAL BIOLOGY.
17,
4
(2021)
Isolation and structural characterization of four diastereomeric lignan glycosides from Abies holophylla and their neuroprotective activity.
TETRAHEDRON.
77,
1
(2020)
Chemical constituents of Chaenomeles sinensis twigs and their biological activity.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY.
16,
1
(2020)
Neurotrophic and anti-neuroinflammatory constituents from the aerial parts of Coriandrum sativum.
BIOORGANIC CHEMISTRY.
105,
1
(2020)
Structure elucidation of small organic molecules by contemporary computational chemistry methods..
ARCHIVES OF PHARMACAL RESEARCH.
43,
11
(2020)
Herqueilenone A, a unique rearranged benzoquinone-chromanone from the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729.
BIOORGANIC CHEMISTRY.
105,
1
(2020)
Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity.
PLANTS-BASEL.
9,
9
수상/공훈
2015.12 : 남강학술상 (한국생약학회)
2014.12 : 우수포스터상 (한국생약학회)
학술회의논문
(2023)
Research for metabolomics using public database.
The 7th Korea Digestive Disease Week.
대한민국
(2023)
Discovery and biosynthesis of imidazolium antibiotics from the probiotic Bacillus licheniformis.
The 143rd Annual Meeting of the Pharmaceutical Society of Japan.
일본
